ALP
The Alkaline Phosphatase (ALP) assay measures the levels of alkaline phosphatase, an enzyme found in various tissues throughout the body, including the liver, bones, and bile ducts. This test plays a critical role in diagnosing liver and bone disorders. Elevated ALP levels may indicate liver disease, bone disorders such as osteoporosis or Paget's disease, or bile duct obstruction. Conversely, low ALP levels are less common but could be associated with malnutrition, hypophosphatasia, or certain genetic conditions. Doctors often include ALP testing as part of routine liver function panels or to monitor bone health in patients undergoing treatment for bone-related conditions.
Sample Requirements:
Gold SST Tube
Stability:
Serum: 7 days 4-25°C
Turnaround Time:
4 hours
Critical Value:
Not Applicable
Assay Interferences:
Recovery within ± 10 %
Icterus: < 10% or 9U/L up to 28mg/dL or 479umol/L bilirubin
Haemolysis: < 10% or 9U/L up to 4.5g/L haemoglobin
Lipemia: < 3% or 9U/L up to 1,000mg/dL intralipid
Reference Range (IU/L):
<1 month: 90.0-260.0 / 1 month - 3 years: 90.0-180.0 / 3-10 years: 130.0-260.0 / 10-14 years: 130.0-340.0 / 14-18 years: 30.0-180.0 / Adult >18 years: 30-130
Known factors:
Decreased ALP
Problem: Incorrect container or anticoagulant
Caused by: K-EDTA contamination